Sinai Health System Researcher Awarded 2019 EASD-Novo Nordisk Foundation Diabetes Prize for Excellence







Monday, September 09, 2019:  Daniel J. Drucker, a senior investigator at Sinai Health System’s Lunenfeld-Tanenbaum Research Institute and a professor of medicine at University of Toronto, was today announced as the 2019 recipient of the EASD-Novo Nordisk Foundation Diabetes Prize for Excellence. 
Dr. Jeff Wrana and team follow a gut feeling and discover a new type of stem cell







Wednesday, April 24, 2019:  A new type of cell has been discovered in the intestinal lining, named the “revival stem cell”. Dr. Wrana, who is a Senior Scientist at the Lunenfeld-Tanenbaum Research Institute, and a team of researchers have found the revival stem cell plays a central role in the regenerative process in the intestine. 
Implication of a placental protein in protection against development of insulin resistance in early life
Tuesday, April 02, 2019:  A placental protein called placental 11 Β-hydroxysteroid dehydrogenase 2 (11Β-HSD2) may protect against the development of T2DM in early life 
Non-invasive detection of certain cancers on the horizon







Wednesday, November 14, 2018:  The realization of the promising field of “liquid biopsy” for cancer detection moved closer this week, with a fascinating new paper published in Nature that measures cancer risk by detecting a type of DNA modification called methylation in circulating DNA in blood 
New Discovery - A built-in killer switch eliminates dividing cells from lab-grown transplant tissue to improve patient safety







Wednesday, November 14, 2018:  Cells hold great potential as medicine but they can’t be trusted in their current form. “Cells that can divide are dangerous by their nature,”... 
Dr. Jeff Wrana Awarded Major Prize for Contributions to Cancer Research







Tuesday, September 18, 2018:  Dr. Jeff Wrana, Senior Investigator at the Lunenfeld-Tanenbaum Research Institute, has been awarded the 2018 McLaughlin Medal by the Royal Society of Canada (RSC), recognizing his pivotal contributions to our understanding of biology, human diseases, and its treatment. The RSC also recognized his leadership in the promotion of “Canadian science through collaborative research facilities and international impact.” Dr. Wrana’s vast accomplishments include delineation of the Transforming Growth Factor beta signal transduction system which plays a key role in cancer development and spread. 
LINE dancing - a new and essential role for repetitive DNA in embryonic development







Thursday, June 21, 2018:  Biologists have long known about segments of repeated sequences of DNA – together such elements comprise almost half of our genomes (and those of other species)... A research team led by Dr. Miguel Ramalho-Santos has now uncovered an important and novel role for the most common of these repetitive elements, called LINE1, which accounts for a full 24% of the human genome.