HOMERESEARCHPUBLICATIONSRESEARCH STAFF

 

 

Welcome to Dr. Rod Bremner Laboratory

 

 
 

 

Bremner, Rod, Ph.D.

Head, Genetics and Development Division
Toronto Western Research Institute

Professor, Departments of Ophthalmology and Lab Med & Pathobiology
University of Toronto

Principal Investigator 
Samuel Lunenfeld Research Institute
Mount Sinai Hospital Joseph & Wolf Lebovic Health Complex
600 University Avenue
Toronto, Ontario M5G 1X5
Canada

Phone: 416-586-4800

Fax: 416-586-8811
Email: click here to send message

 

 
 

 

This movie shows a 3D view of a clone of cells in the mouse retina (from work by M Pacal in the lab). A retrovirus expressing a fluorescent protein (GFP) was injected into the retina. The concentration of virus particles is low enough to ensure that only rare progenitors take up virus. The progenitor in this case gave rise to three daughter neurons. This occurs when the dividing progenitor generates one post-mitotic daughter neuron and a progenitor, then the latter gives rise to two post-mitotic neurons. The blue and purple cells are rod photoreceptors and the yellow cell is a bipolar interneuron. Photoreceptors communicate with bipolar cells through extensive synaptic connections.