Past Lab Members

Peggy Clark

Presently:
Elementary Teacher

Mona Cui

Xiao-Ping Jin

Presently:
Physiotherapist

Ruth MacLachlan

Presently:
Manager, Regulatory affairs

Rita Nespeca

Presently:
Statistical Analyst

Jindra Tupy

Presently:
Researcher

Dr. Mircea Dumitriu

September 1990-2010

Thesis:
Image analysis using mathematical morphology

Presently:
Retired

Danielle DiLeo

September - December 2012

Christine McCaul

April - June 2013

Tanya Raaphorst

September 2013 - August 2014

Presently:
PhD candidate

Carol Chahine

Mehran Kasra

October 1990 - March 1998

Presently:
Assistant Professor
Department of Biomedical Engineering Dept of Biomedical Engineering
McMaster University

Danmei Liu

September 1998 - October 2000

Presently:
Research Associate
Vancouver General Hospital

Stephen Waldman

September 1999 - March 2002

Presently:
Professor
Department of Mechanical and Materials Engineering
Queen's University

Luisa Moreno

September 2003 - November 2006

Presently:
Business Development Associate, Ontario Centres of Excellence

Jian Wang

September 2006 - April 2008

Presently:
Supervisor
Department of Dentistry
University of Toronto

Thomas Willett

September 2009 - August 2011

Thesis:
The Sensitivity of Bone Fracture Resistance to Advanced Glycation Endproducts

Bedilu Allo

September 2014 - July 2015

Thesis:
Developing biodegradable orthopedic implants for load-bearing applications

Kathleen Lundon

September 1990 - January 1994

Thesis:
The differential effects of altered levels of sex steroid hormones on the skeleton in the young female Cynomologus monkey

Presently:
Assistant Professor
Department of Physical Therapy, Faculty of Medicine
University of Toronto

Antonietta Cerroni

September 1990 - March 2000

Thesis:
The pathology and epidemiology of spontaneous diseases and disorders of the spine in the rhesus macaques of Cayo Santiago

Presently:
Lecturer
Department of Anthropology
University of Toronto

Sabrina Agarwal

September 1994 - March 2001

Thesis:
The influence of age and sex on trabecular architecture and bone mineral density in three British historical populations

Presently:
Assistant Professor
Department of Anthropology
University of California Berkeley

Debbie Chachra

September 1995 - March 2001

Thesis:
The influence of long-term exposure to environmental fluoride on bone quality in humans

Presently:
Assistant Professor
Department of Materials Science
Olin College of Massachusetts

Anya Vieira

January 2001 - August 2004

Thesis:
Fluoride, dental fluorosis and tooth quality

Presently:
Professor
Department of Education and Health Master Program
Universidade de Fortaleza

Sidney Omelon

September 2000 - 2006

Thesis:
Material properties and in vitro and in vivo degradation of calcium polyphosphate

Presently:
Assistant Professor
Department of Materials Science Engineering
University of Ottawa

Lisa Wise

September 2001 - March 2007

Thesis:
Differential effects of two pro-apoptotic members of the bcl-2 gene family on murine bone quality

Presently:
Research associate
Sunnybrook Hospital
University of Toronto

Chrystia Wynnyckyj

September 2005 - 2010

Thesis:
The consequences of collagen degradation on bone mechanical properties

Presently:
Engineer

Fred Nicholls

May 2010 - 2011

Thesis:
The Effects of Ionizing Radiation and Periosteal Stripping on Rat Bone

Stephanie Goldberg

September 2009- May 2015

Thesis:
Assess the role of Rac1 and Rac2 in regulating osteoclastogenesis and bone turnover in vivo

Adeline Ng

September 2009- April 2015

Thesis:
Development, Validation and Characterization of a Mouse Model of Adynamic Bone Disease (ABD)

Eilis Hamilton

May - August 1991

Thesis:
The combined effect of F and Sr on bone mineralization

Caprice Boisvert

May - August 1992

Thesis:
The mechanical properties of cortical bone from ovariectomized and estrogen/progesterone repleted rats

Brian Lam

May - August 1992

Thesis:
The effect of acidosis on bone mineral

Irene Koo

May - August 1994

Thesis:
Backscattered Electron Imaging (BSE) of subchondral bone in a dog

Irene Koo

May - August 1995

Thesis:
Comparison of spontaneous oa in humans and non-humans primates

Katherine Sodek

May - August 1995

Thesis:
Bone protein maturation in a fetal pig model

Kristina Kukk

May - August 1997

Thesis:
Changes in the mechanical properties of bones in OPN knock-out mice

Kerry OBrien

May - August 1998

Thesis:
Does a correlation exists between the vertebral compressive failure load and the curvature of the cortical wall

Jacek Strzelczyk

May - August 1999

Thesis:
Aseptic loosening guelph canine study: Backscattered Electron (BSE) imaging

Jeanette deMontmorency

May - August 2000

Thesis:
Stiffness determination of bone hardness, differences in quadrant hardness and effects bisphosphonates have on the canine femur

Jennifer Tang

May - August 2000

Thesis:
Investigation of increasing doses of zoledronate effects on cortical bone structure in the canine model

Jessica Currie

May - August 2001

Thesis:
Effects of fluoride on bone quality in osteoarthritic patients

Fred Nicholls

May - August 2001

Thesis:
Fetuin effects on the properties of bone

Paul Frydrych

May - August 2002

Thesis:
Factors determining bone quality in recombinant inbred mouse strains from progenitors C57BL/6J (B6) and C3H/HeJ (C3H)

Cindy Wong

May - August 2002

Thesis:
The effect of grain size on the tensile strength of porous calcium polyphosphate (CPP)

Justin Fung

May - August 2003

Thesis:
Modifying the mechanical properties of calcium polyphosphate using sodium and potassium dopants

Ian McRobie

May - August 2003

Thesis:
Effect of soaking 2 different calcium polyphosphate sintered constructs in cell culture media on the construct mechanical properties

Tanya Hunt

May - August 2004

Thesis:
Strain and gender dependent effects on bone quality of harakiri (HRK)-deficient Mice

Rasha Ashraf

May - August 2010

Thesis:
MicroCT analyses of rat bone architecture

Nick Diggins

June - August 2011

Thesis:
Design of a Novel Mechanical Testing Fixture for the Assessment of Superior Acetabulum Defects

Neelie Zacharias

May - August 2011

Thesis:
Quantifying Advanced Glycation Endproducts (AGE) Using Reverse-Phase High-Performance Liquid Chromatography

Emily Labrakos

September 1993 - May 1994

Thesis:
The changes in bone mechanical properties due to equine osteochondritis

Steven Ekstein

September 1997 - May 1998

Thesis:
A finite element model of the spine I

Mark Timmer

September 1997 - May 1998

Thesis:
A finite element model of the spine II

Joanne Farrington

September 1998 - May 1999

Thesis:
The effect of arthritis on viscoelastic properties of femoral head trabecular bone

Elliot Lew

September 1998 - May 1999

Thesis:
The effects of fluoride on bone proteins

Faryab Zargar

September 1998 - May 1999

Thesis:
A finite element model of the intervertebral disc

Owen Clarke

September 1999 - May 2000

Thesis:
A finite element model of the spine III

Arezou Ghahramani

September 2000 - May 2001

Thesis:
Finite element modeling and analysis of the human lumbar vertebra

Suzanne Given

September 2000 - May 2001

Thesis:
Mechanical properties of osteoarthritic human femoral head cancellous bone

Sachi Hasan

September 2001 - May 2002

Thesis:
Designing a method for measuring the dissolution rate of gypsum (calcium sulphate dihydrate) in solution

Fred Nicholls

September 2001 - May 2002

Thesis:
Backscattering electron microscopy and elemental chemical analysis in the study of aseptic loosening of hip implants in dogs

Alice Wu

September 2004 - May 2005

Thesis:
Failure of rat vertebrae due to cyclic loading

Leona Smith

September 2007 - May 2008

Thesis:
The long term investigation of the interactions between bisphosphonates and fluoride in trabecular bone within and between inbred strains of mice

Cara Fallis

September 2010 - August 2011

Thesis:
Development of an Animal Model of Radiation-Associated Fracture and Subsequent Intervention with Osteogenic Protein-1

Christopher Tranquada

September 2010 - May 2011

Thesis:
Effect of Advanced Glycation End-Products on Cortical Bone Toughness and Fatigue Resistance

Sushila Lucas

January 1986 - 1988

Thesis:
Experimental arthritis in a rabbit model

Presently:
Teacher

Angela Acito

September 1989 - 1992

Thesis:
The effects of APD treatment on the structural and mechanical properties of canine cortical bone

Presently:
Validation Engineer

Nancy Podworny

September 1995 - 1997

Thesis:
Bone and cartilage destruction in an animal model of inflammatory arthritis

Presently:
Physiotherapist

Tim Woodfield

September 1997 - 1999

Thesis:
Experimental and modeling studies of the temporomandibular joints

Presently:
Assistant Professor
Centre for Bioengineering &Department of Orthopaedic Surgery
University of Canterbury

Clara Kwan

September 2000 -

Thesis:
Mechanical properties of intervertebral discs

Presently:
In Memory (Jan 14/75 - May 30/01)

Lilian Lee

September 1998 - 2001

Thesis:
The effect of BAP on the bone of mature ovariectomized rats

Presently:
Technician

Jennifer Lee

September 1998 - 2001

Thesis:
The effect of BAP on the uterus and the bone of young growing rats

Presently:
Sales - Territory Manager

Christina Djokoto

September 2000 - 2002

Thesis:
The optimization of a Mechanical Response Tissue Analyzer (MRTA) and a descriptive comparison with dual energy x-ray absorptiometry and quantitative ultrasound

Presently:
Clinical Engineer

Adeline Ng

September 2000 - 2003

Thesis:
Trace elements and bone quality in renal osteodystrophy

Presently:
PhD candidate
Laboratory Medicine & Pathobiology
University of Toronto

Erin Fawcett

January 2002 - 2004

Thesis:
The skeletal effects of a growth hormone-derived peptide (AOD9604) in the aged rat model of postmenopausal osteoporosis

Presently:
Account Manager

Diana Facchini

September 2002 - 2005

Thesis:
The effects of vandium on bone quality in rat models of diabetes and postmenpausal osteoporosis

Presently:
Research Engineer

Andrew Chui

September 2004 - 2006

Thesis:
Vanadium treatment prevents bone loss and maintains bones quality in a combined osteoporosis and diabetes rat model

Presently:
Hedge Fund Accountant

Tayyab Khan

September 2004 - 2006

Thesis:
Longitudinal characterization of bone quality in Sca-1 null mice

Presently:
Medical School Student

Tanya Hunt

September 2005 - 2007

Thesis:
Can Vitamin D delay or arrest the progression of osteo-arthritis in an animal model

Presently:
Engineer

Libby Rowe

January 2005 - 2007

Thesis:
Can a growth hormone-derived peptide (AOD9604) prevent bone loss and fragility in a rat model of osteoporosis?

Presently:
Site Manager

Ivan Kamikovski

January 2007 - 2009

Thesis:
The skeletal effects of a growth hormone-derived peptide (AOD9604) in the aged rat model of post-menopausal osteoporosis Phase III

Presently:
Medical School Student

Judy Ue

September 2005 - 2009

Thesis:
The effect of doping on the degradation of calcium polyphosphate

Presently:
Project co-ordinator

Nastaran Abbarin

September 2008 - 2010

Thesis:
Effect of Potassium and Magnesium Doping on Sintering and Properties of Calcium Polyphosphate

Presently:
PhD candidate

Kimberly Kyle

September 2008 - 2010

Thesis:
Differential Effects of PPAR-? Activation vs. Chemical or Genetic Reduction of DPP-4 Activity on Murine Bone Quality

Presently:
Regulatory affairs associate

Joyce Magalhaes

September 2008 - 2010

Thesis:
Determining the role of Rac1 and Rac2 in the bone quality of an aged and osteoporotic female mouse model

Presently:
Medical School

Laura Sardone

September 2008 - 2010

Thesis:
The Effect of Rosiglitazone on Bone Quality in a Rat Model of Insulin Resistance and Osteoporosis

Presently:
Teacher

Herman Thang

January 2007 - 2010

Thesis:
Assess the role of Rac1 and Rac2 in osteoporosis using a male mouse model

Presently:
Dentist

Brianne Burton

September 2011 - 2013

Thesis:
Improving the Mechanical Properties of Irradiation Sterilized Bone Allografts

Presently:
Physiotheraphy student

Anne Gaspar

January 2011 - 2013

Thesis:
Beyond Bone Mineral Density: Assessment of Fracture Risk with the Mechanical Response Tissue Analyzer

Careesa Liu

September 2011- 2013

Thesis:
Effect of conjugate bisphosphonate and EP4 receptor agonist in treatment of osteoporosis in ovariectomized rats

Presently:
PhD student

Sally Hu

September 2012- 2014

Thesis:
Can OP-1 Stimulate Union in a Rat Model of Pathological Fracture Post Treatment for Soft Tissue Sarcoma?

Presently:
Medical student

Katarina Janic

September 2011- 2014

Thesis:
The Effects of Ionizing Radiation and Periosteal Stripping on Rat Bone Fracture Post Treatment for Soft Tissue Sarcoma?

Presently:
Medical student

Chris Kim

September 2013- 2014

Thesis:
The Restorative Effects of Deferoxamine on Neoangiogenesis Post-Irradiation

Presently:
Physician

Seanna Yoon

September 2012- 2014

Thesis:
Growth arrest and osteoporosis in Duchenne muscular dystrophy

Veronica Ciolfi

May - December 1998

Thesis:
Role of corticosteroids in weightlessness-induced bone loss

Jennifer Boger

May - August 1999

Thesis:
Exploration of the effect of cyclic hydrostatic loading on rat bone marrow cells

Lisa Wise

January - August 1999

Thesis:
The effect of zoledronate on bone quality in the treatment of aseptic loosening of canine hip replacements

Jennifer Boger

January - August 2000

Thesis:
HMR vitronectin receptor inhibitor effects on bone

Adele Changoor

January - August 2001

Thesis:
Biomechanical tests to determine the effects of a vitronectin receptor inhibitor on the mechanical properties of rat bones

Winnie Lai

January - August 2002

Thesis:
Determining the quality of bone in a rat model of osteoporosis

Arani Kajenthira

January - August 2003

Thesis:
Examination of the skeletal phenotype of mice that were bred for high and low red blood cell (RBC) magnesium levels

Katie Stuart

January - August 2003

Thesis:
The skeletal phenotype of high and low magnesium mice

Priya Bhola

January - August 2004

Thesis:
Differences in bone fragility among 5 inbred mice strains

Stephanie Neufeld

January - August 2006

Thesis:
The effects of n-butyryl glucosamine on bone quality in an ovariectomized rat model

Jamie Greenfield

May - August 2009

Thesis:
Bone quality in a mouse model of adynamic bone disease

Christine Barker

September - December 2010

Thesis:
The Sensitivity of Bone Fracture Resistance to Advanced Glycation End Products

Madison Cohen-McFarlane

January - August 2013

Thesis:
Effect of Potassium Citrate on BMD and Bone Quality

Elise Post

January - August 2014

Thesis:
Effects of normal calcium diet and low sodium on stone formation and bone resorption

Amy Vandeneynde

January - August 2015

Thesis:
Effects of Normal Na and Low Na Diet on Stone Formation and Bone Resorption

Josephine Yee

January - August 2015

Thesis:
The role of PTH in the ability of exercise to increase bone mineral density and strength

Raquel Lopez

May - December 2002

Thesis:
An in vivo study of the degradation of two forms of calcium polyphosphates (nano-crystal and micro-crystal) for bone substitute applications

Ryan Mui

January - August 2003

Thesis:
Bone and cartilaginous changes in the disease progression of an accelerated osteoarthritis animal mode

Ryan Formosa

January - August 2004

Thesis:
Characterize the relationship between subchondral bone changes and cartilage degeneration progression in the guinea pig animal model

Christine How

January - August 2004

Thesis:
Characterization of biochemical changes in cartilage in the progression of osteoarthritis in the guinea pig model

Anna Phan

January - August 2004

Thesis:
The changes in subchondral bone during OA and bisphosphonate treatment of OA in a guinea pig model

Annie Cherian

January - August 2005

Thesis:
Effects of glucosamine hydrochloride treatment on an osteoarthritis induced model in the rabbit

Abhijat Kitchlu

January - August 2005

Thesis:
Emu bone composition and deproteination

Natalya Kruglyak

January - August 2006

Thesis:
A longitudinal study of bone quality in a mouse model of oculodentodigital dysplasia

Kimberly Kyle

January - August 2007

Thesis:
Parity prediction utilizing monkey rib samples

Lauren McShane

January - August 2007

Thesis:
The long term investigation of the interactions between bisphosphonates and fluoride in trabecular bone within and between inbred strains of mice. A pilot study

Laura Sardone

January - August 2007

Thesis:
The long term investigation of the interactions between bisphosphonates and fluoride in cortical bone within and between inbred strains of mice. A pilot study

Vesna Mihajlovic

May - August 2008

Thesis:
Effect of Rosiglitazone treatment on bone loss and bone quality in rat models of Type 2 diabetes and osteoporosis

Rushika Perera

May - August 2008

Thesis:
Effect of Rosiglitazone treatment on bone loss and bone quality in rat models of Type 2 diabetes and osteoporosis

Joyce Wan

January - August 2008

Thesis:
Study of the bone phenotype of the ob/ob: Glp2r -/- mouse

Michelle Chan

January - August 2009

Thesis:
Sex differences in bone adaptation to mechanical loading in an In-vivo rabbit tibia model

Sara Che

January - August 2009

Thesis:
Effects of Chlorthalidone on bone quality of genetic hypercalciuric stone-forming (GHS) rats

Raymond Ho

January - August 2009

Thesis:
Determine the mechanism of mineral-matrix interface debonding and/or collagen degradation due to KOH treatment

Diana Mester

September - December 2009

Thesis:
An assay for measuring advanced glycation endproducts in bone collagen

Jon Bain

September - December 2010

Thesis:
The Effects of Ionizing Radiation and Periosteal Stripping on Rat Bone

Sabrina Stanley

January - August 2010

Thesis:
The Effects of Ionizing Radiation and Periosteal Stripping on Rat Bone

Natasha Szabolcs

January - August 2010

Thesis:
Determining Bone Adaptive Response to Mechanical Loading: Development of an In Vivo Rabbit Tibia Model Trial #2

Natashah Zaver

September 2009 - April 2010

Thesis:
Determining Bone Adaptive Response to Mechanical Loading: Development of an In Vivo Rabbit Tibia Model Trial #2

Angelica Chan

January - August 2011

Thesis:
Are low doses of lithium anabolic to bone but high doses of lithium may negatively affects bone quality

Sibi Sutty

January - August 2011

Thesis:
The Sensitivity of Bone Fracture Resistance to Advanced Glycation End Products

Tiffany Ho

January - August 2012

Thesis:
The effect of calcitriol on bone quality in genetic hypercalciuric stone-forming rats

David Josey

January - August 2012

Thesis:
Detecting and Quantifying Microdamage in Cortical Bone using microCT

Doo Hwan Oh

January - August 2012

Thesis:
Commercialization of Irradiation-Sterilized Bone Allografts with Enhanced Mechanical Properties

Xing Ze Lu

January - August 2015

Thesis:
Effect of Ribose and Annealing on the Free Radical Content and Mechanical Properties of ?-Irradiation Sterilized Bone

Gagan Minhas

January - August 2015

Thesis:
Effect of Ribose and Annealing on the Free Radical Content and Mechanical Properties of ?-Irradiation Sterilized Bone

Keertika Yogendirarajah

January - August 2015

Thesis:
The role of LXR antagonism in glucocorticoid-induced osteoporosis using a Cushingoid mouse model

Gwenael Fraslin

January - June 1993

Thesis:
The effect of estrogens and progestins on bone quality and quantity in the aged ovariectomized rat model of osteoporosis

Anne Gouinguene

July - December 1993

Thesis:
Changes in mineralization in human bone biopsies with fluoride treatment

Isabelle Catelas

January - June 1994

Thesis:
Effects of bisphosphonates on the mechanical properties of bone

Morgane LaPlace

July - December 1994

Thesis:
Bone aging in free ranging Rhesus monkeys

Christelle Hermet

January - June 1995

Thesis:
Effects of a new drug CGP42'446, third generation of bisphosphonate, on mechanical properties of canine bone

Marianne Manot

July - December 1995

Thesis:
Study of the effects of a third generation bisphosphonate on the mechanical properties of rat bone

Claire Jegou

January - June 1996

Thesis:
Examination of the toxicology of a new drug, CGP 42 446, third generation of bisphosphonate, on mechanical properties of canine bone treated during 1 year, and of canine bone treated during one year followed by 6 months of recovery

Celine Winter

July - December 1996

Thesis:
The influence of different treatments on the mechanical properties of bone

Florence Duhamel

July - December 1997

Thesis:
Effects of over-expressed fetuin gene on bone mechanical properties

Claire Chedeville

January - June 1998

Thesis:
Studies on the mechanical properties of bone from knock-out mice

Marion Elbel

July - December 1999

Thesis:
The effect of zoledronate on bone quality in the treatment of aseptic loosening of hip arthroplasty in canines

Gaelle LeMur

January - June 1999

Thesis:
Study of the effects of the absence of the osteoprotegerin ligand expression (OPGL) on mice bone mechanical properties

Sylvie Mandirac

July - December 2000

Thesis:
The effect of zoledronate on bone quality in the treatment of aseptic loosening in a canine model

Tiphaine LePort

July - December 2001

Thesis:
The effect of BaP:DMBA on the mechanical properties of rat bones

Julien Coulomb

July - December 2002

Thesis:
Effect of glucosamine on bone in a model of osteoarthritis

Nathalie Poey

January - June 2002

Thesis:
Bone quality of Ly-6A knock-out mice

Marie-Claire Andrieu

July - December 2004

Thesis:
An in vivo study of the degradation of two forms of calcium polyphosphates (nano-crystal and micro-crystal) for bone substitute application