Publications
208. Teta M, Choi YS, Okegbe T, Wong G, Tam OH, Chong MM, Seykora JT, Nagy A, Littman DR, Andl T, Millar SE. (2012) Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin. Development. 2012 Apr;139(8):1405-16.
207. Ji J, Ng SH, Sharma V, Neculai D, Hussein S, Sam M, Trinh Q, Church GM, McPherson JD, Nagy A, Batada NN. (2011) Elevated Coding Mutation Rate During the Reprogramming of Human Somatic Cells into Induced Pluripotent Stem Cells.Stem Cells. 2011 Dec 12. doi: 10.1002/stem.1011. [Epub ahead of print]
205. Puri MC, Nagy A. (2011) Concise Review: ES vs. iPS Cells; the Game is on. Stem Cells. 2011 Nov 18. doi: 10.1002/stem.788. [Epub ahead of print]
204. Mathieu Gabut, Payman Samavarchi-Tehrani, Xinchen Wang, Valentina Slobodeniuc, Dave O'Hanlon, Hoon-Ki Sung, Manuel Alvarez, Shaheynoor Talukder, Qun Pan, Esteban O. Mazzoni, Stephane Nedelec, Hynek Wichterle, Knut Woltjen, Timothy R. Hughes, Peter W. Zandstra, Andras Nagy, Jeffrey L. Wrana, Benjamin J. Blencowe (2011) An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming. Cell, 15 September 2011
203. Woltjen K, Hämäläinen R, Kibschull M, Mileikovsky M, Nagy A. (2011) Transgene-Free Production of Pluripotent Stem Cells Using piggyBac Transposons. Methods Mol Biol. 2011;767:87-103.
202. Mohseni P, Sung HK, Murphy AJ, Laliberte CL, Pallari HM, Henkelman M, Georgiou J, Xie G, Quaggin SE, Thorner PS, Eriksson JE and Nagy A. (2011) Nestin is not essential for development of the central nervous system but required for dispersion of acetylcholine receptor clusters at the area of neuromuscular junctions. J Neurosci. 2011 Aug 10;31(32):11547-11552.
201. Nishino K, Hattori N, Sato S, Arai Y, Tanaka S, Nagy A, Shiota K. (2011) Non-CpG Methylation Occurs in the Regulatory Region of the Sry Gene. J Reprod Dev. 2011 Jun 3. [Epub ahead of print] 
200. Adachi H, Kondo T, Koh GY, Nagy A, Oike Y, Araki E. (2011) Angptl4 deficiency decreases serum triglyceride levels in low-density lipoprotein receptor knockout mice and streptozotocin-induced diabetic mice. Biochem Biophys Res Commun. 2011 Apr 28. [Epub ahead of print]
199. Hussein SM, Nagy K, Nagy A. (2011) Human Induced Pluripotent Stem Cells: The Past, Present, and Future, Clinical Pharmacology & Therapeutics , (23 March 2011) | doi:10.1038/clpt.2011.37
198. Hussein SM, Batada NN, Vuoristo S, Ching RW, Autio R, Närvä E, Ng S, Sourour M, Hämäläinen R, Olsson C, Lundin K, Mikkola M, Trokovic R, Peitz M, Brüstle O, Bazett-Jones DP, Alitalo K, Lahesmaa R, Nagy A, Otonkoski T. (2011) Copy number variation and selection during reprogramming to pluripotency. Nature. 2011 Mar 3;471(7336):58-62.
197. Nagy K,
Sung HK, Zhang P, Laflamme S, Vincent P, Agha-Mohammadi S, Woltjen K,
Monetti C, Michael IP, Smith LC, Nagy A. (2011) Induced Pluripotent
Stem Cell Lines Derived from Equine Fibroblasts. Stem
Cell Rev. 2011 Feb 24. [Epub ahead of print]Erratum to: Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts.
196. Guorui Huang, Gaoxiang Ge, Dingyan Wang, Bagavathi Gopalakrishnan, Delana H. Butz, Ricki J. Colman, Andras Nagy, Daniel S. Greenspan (2011) α3(V) Collagen is critical for glucose homeostasis in mice due to effects in pancreatic islets and peripheral tissues. J. Clin. Invest. 2011; doi:10.1172/JCI45096
195. Monetti C, Nishino K, Biechele S, Zhang P, Baba T, Woltjen K, Nagy A. (2010) PhiC31 integrase facilitates genetic approaches combining multiple recombinases. Methods. 2010 Dec 22. [Epub ahead of print]
194. Hardouin SN, Guo R, Romeo PH, Nagy A, Aubin JE. (2010) Impaired mesenchymal stem cell differentiation and osteoclastogenesis in mice deficient for Igf2-P2 transcripts. Development. 2010 Dec 9. [Epub ahead of print]
193. Tonge PD, Nagy A. (2010) Extinction of Xist improves cloning. Cell Stem Cell. 2010 Nov 5;7(5):550-2.
192. Kibschull M, Mileikovsky M, Michael IP, Lye SJ, Nagy A. (2010) Human embryonic fibroblasts support single cell enzymatic expansion of human embryonic stem cells in xeno-free cultures. Stem Cell Res. 2010 Aug 27. [Epub ahead of print]
191. Koh YJ, Kim HZ, Hwang SI, Lee JE, Oh N, Jung K, Kim M, Kim KE, Kim H, Lim NK, Jeon CJ, Lee GM, Jeon BH, Nam DH, Sung HK, Nagy A, Yoo OJ, Koh GY. (2010) Double Antiangiogenic Protein, DAAP, Targeting VEGF-A and Angiopoietins in Tumor Angiogenesis, Metastasis, and Vascular Leakage. Cancer Cell. 2010 Aug 9;18(2):171-184.
190. Nagy A, Nagy K, Gertsenstein M. (2010) Production of mouse chimeras by aggregating pluripotent stem cells with embryos. Methods Enzymol. 2010;476:123-49.
189.
Gertsenstein M, Nutter LM, Reid T, Pereira M, Stanford WL, Rossant J,
Nagy A. (2010) Efficient generation of germ line transmitting
chimeras from C57BL/6N ES cells by aggregation with outbred host embryos. PLoS
One. 2010 Jun 22;5(6):e11260.
188. Drogat B, Kalucka J, Gutiérrez L, Hammad H, Goossens S, Farhang Ghahremani M, Bartunkova S, Haigh K, Deswarte K, Nyabi O, Naessens M, Ferrara N, Klingmüller U, Lambrecht B, Nagy A, Philipsen S, Haigh JJ. (2010) VEGF regulates embryonic erythroid development through GATA1 modulation. Blood. 2010 Jun 16. [Epub ahead of print]
187. Samavarchi-Tehrani P, Golipour A, David L, Sung HK, Beyer TA, Datti A, Woltjen K, Nagy A, Wrana JL (2010) Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming. Cell Stem Cell. 2010 Jul 2;7(1):64-77. Epub 2010 Jun 17.
186. Nagy A, Quaggin SE. (2010) Stem Cell Therapy for the Kidney: A Cautionary Tale. J Am Soc Nephrol. 2010 Jun 17. [Epub ahead of print]
185. Liu F, Dangaria S, Andl T, Zhang Y, Wright AC, Damek-Poprawa M, Piccolo S, Nagy A, Taketo M, Diekwisch TG, Akintoye SO, Millar SE. (2010) {beta}-catenin Initiates Tooth Neogenesis in Adult Rodent Incisors. J Dent Res. 2010 Jun 8. [Epub ahead of print]
184. Tardif S, Wilson MD, Wagner R, Hunt P, Gertsenstein M, Nagy A, Lobe C, Koop BF, Hardy DM. (2010) Zonadhesin is essential for species specificity of sperm adhesion to the egg's zona pellucida. J Biol Chem. 2010 Jun 7. [Epub ahead of print]
183. Hai B, Yang Z, Millar SE, Choi YS, Taketo MM, Nagy A, Liu F. (2010) Wnt/beta-catenin signaling regulates postnatal development and regeneration of the salivary gland. Stem Cells Dev. 2010 Mar 30. [Epub ahead of print]
182. Coultas L, Nieuwenhuis E, Anderson GA, Cabezas J, Nagy A, Henkelman RM, Hui CC, Rossant J. (2010) Hedgehog regulates distinct vascular patterning events through VEGF dependent and independent mechanisms. Blood. 2010 Mar 25. [Epub ahead of print]
181. Sung HK, Michael IP, Nagy A. (2010) Multifaceted role of vascular endothelial growth factor signaling in adult tissue physiology: an emerging concept with clinical implications. Curr Opin Hematol. 2010 Mar 4. [Epub ahead of print] PMID: 20216210 [PubMed - as supplied by publisher]
180. Vecchiarelli-Federico LM, Cervi D, Haeri M, Li Y, Nagy A, Ben-David Y. (2010) Vascular endothelial growth factor--a positive and negative regulator of tumor growth. Cancer Res. 2010 Feb 1;70(3):863-7. Epub 2010 Jan 26.
179. Yamanaka N, Wong CJ, Gertsenstein M, Casper RF, Nagy A, Rogers IM. (2009) Bone marrow transplantation results in human donor blood cells acquiring and displaying mouse recipient class I MHC and CD45 antigens on their surface. PLoS One. 2009 Dec 31;4(12):e8489.
178. Nagy A, Nagy K (2009) The mystery of induced pluripotency: where will they lead? Nature Methods. [Epub ahead of print] - Commentary, Special feature
177. Maes C, Goossens S, Bartunkova S, Drogat B, Coenegrachts L, Stockmans I, Moermans K, Nyabi O, Haigh K, Naessens M, Haenebalcke L, Tuckermann JP, Tjwa M, Carmeliet P, Mandic V, David JP, Behrens A, Nagy A, Carmeliet G, Haigh JJ. (2009) Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones. EMBO J.. [Epub ahead of print]
176. Ahmed N, Taylor DW, Wunder J, Nagy A, Gross AE, Kandel RA. J (2009) Passaged human chondrocytes accumulate extracellular matrix when induced by bovine chondrocytes. Tissue Eng Regen Med. 2009 Dec 8. [Epub ahead of print]
175. Xu K, Nieuwenhuis E, Cohen BL, Wang W, Canty AJ, Danska JS, Coultas L, Rossant J, Wu MY, Piscione TD, Nagy A, Gossler A, Hicks GG, Hui CC, Henkelman RM, Yu LX, Sled JG, Gridley T, Egan SE. (2009) Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. Am J Physiol Lung Cell Mol Physiol. 2010 Jan;298(1):L45-56. Epub 2009 Nov 6.
174. Giuffrida D, Rogers IM, Nagy A, Calogero AE, Brown TJ, Casper RF. (2009) Human embryonic stem cells secrete soluble factors that inhibit cancer cell growth. Cell Prolif. 2009 Sep 1. [Epub ahead of print]
173. Louis Lefebvre; Lynn Mar; Aaron Bogutz; Rosemary Oh-McGinnis; Mohammad Mandegar; Jana Paderova; Marina Gertsenstein; Jeremy A. Squire; Andras Nagy (2009) The interval between Ins2 and Ascl2 is dispensable for imprinting centre function in the murine Beckwith-Wiedemann region. Human Molecular Genetics 2009; doi: 10.1093/hmg/ddp379
172. Godmann M, Gashaw I, Katz JP, Nagy A, Kaestner KH, Behr R. (2009) Krüppel-like factor 4, a "pluripotency transcription factor" highly expressed in male postmeiotic germ cells, is dispensable for spermatogenesis in the mouse. Mech Dev. 2009 Jun 17. [Epub ahead of print]
171. Ivics Z, Li MA, Mátés L, Boeke JD, Nagy A, Bradley A, Izsvák Z. (2009) Transposon-mediated genome manipulation in vertebrates. Nat Methods. 2009 Jun;6(6):415-22.
170. Nyabi O, Naessens M, Haigh K, Gembarska A, Goossens S, Maetens M, De Clercq S, Drogat B, Haenebalcke L, Bartunkova S, De Vos I, De Craene B, Karimi M, Berx G, Nagy A, Hilson P, Marine JC, Haigh JJ. (2009) Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells. Nucleic Acids Res. 2009 Mar 11. [Epub ahead of print]
169. Tanaka M, Hadjantonakis AK, Vintersten K, Nagy (2009) Aggregation Chimeras: Combining ES Cells, Diploid, and Tetraploid Embryos. A. Methods Mol Biol. 2009;530:1-23.
168. Nagy A, Mar L, Watts G.(2009) Creation and use of a cre recombinase transgenic database. Methods Mol Biol. 2009;530:1-14.
167. Ellis J, Bruneau BG, Keller G, Lemischka IR, Nagy A, Rossant J, Srivastava D, Zandstra PW, Stanford WL. (2009) Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell. 2009 Mar 6;4(3):198-9; author reply 202. No abstract available.
166. Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, Hämäläinen R, Cowling R, Wang W, Liu P, Gertsenstein M, Kaji K, Sung HK, Nagy A. (2009) piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature. 2009 Mar 1. [Epub ahead of print]
165. Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, Woltjen K. (2009) Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature. 2009 Mar 1. [Epub ahead of print]
164. Adachi H, Fujiwara Y, Kondo T, Nishikawa T, Ogawa R, Matsumura T, Ishii N, Nagai R, Miyata K, Tabata M, Motoshima H, Furukawa N, Tsuruzoe K, Kawashima J, Takeya M, Yamashita S, Koh GY, Nagy A, Suda T, Oike Y, Araki E. (2008) Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis. Biochem Biophys Res Commun. 2008 Dec 16. [Epub ahead of print]
163. Hadjantonakis AK, Pirity M, Nagy A. (2008) Cre recombinase mediated alterations of the mouse genome using embryonic stem cells. Methods Mol Biol. 2008;461:111-32. Review. No abstract available.
162. Ahmed N, Gan L, Nagy A, Zheng J, Wang C, Kandel RA. (2008) Cartilage Tissue Formation Using Redifferentiated Passaged Chondrocytes In Vitro. Tissue Eng Part A. 2008 Sep 10. [Epub ahead of print]
161. Purpura KA, George SH, Dang SM, Choi K, Nagy A, Zandstra PW. (2008) Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner. Stem Cells. 2008 Nov;26(11):2832-42. Epub 2008 Sep 4.
160. Séguin CA, Draper JS, Nagy A, Rossant J. (2008) Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells. Cell Stem Cell. 2008 Aug 7;3(2):182-95.
159. Zhang Y, Andl T, Yang SH, Teta M, Liu F, Seykora JT, Tobias JW, Piccolo S, Schmidt-Ullrich R, Nagy A, Taketo MM, Dlugosz AA, Millar SE.(2008) Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate. Development. 2008 Jun;135(12):2161-72. Epub 2008 May 14.
158. Alberti K, Davey RE,
Onishi K, George S, Salchert K, Seib FP, Bornhäuser M, Pompe T,
Nagy A, Werner C, Zandstra PW. (2008) Functional immobilization of signaling
proteins enables control of stem cell fate. Nat
Methods. 2008 Jun 15.
157. Cohen CB, Brandhorst B, Nagy A, Leader A, Dickens B, Isasi RM, Evans D, Knoppers BM. (2008) The use of fresh embryos in stem cell research: ethical and policy issues. Cell Stem Cell. 2008 May 8;2(5):416-21.
156. O'Connor MD, Kardel MD, Iosfina I, Youssef D, Lu M, Li MM, Vercauteren S, Nagy A, Eaves CJ. (2008) Alkaline Phosphatase-positive Colony Formation is a Sensitive, Specific and Quantitative Indicator of Undifferentiated Human Embryonic Stem Cells. Stem Cells. 2008 Feb 14; [Epub ahead of print] PMID: 18276800
155. Kolodziejska KM, Ashraf HN, Nagy A, Bacon A, Frampton J, Xin HB, Kotlikoff MI, Husain M. (2008) c-Myb Dependent Smooth Muscle Cell Differentiation. Circ Res. 2008 Jan 10; [Epub ahead of print] PMID: 18187733
154. Wilson MD, Wang D, Wagner R, Breyssens H, Gertsenstein M, Lobe C, Lu X, Nagy A, Burke RD, Koop BF, Howard PL. (2007) Ars2 is a conserved eukaryotic gene essential for early mammalian development. Mol Cell Biol. 2007 Dec 17; [Epub ahead of print]
153. Oh R, Ho R, Mar L, Gertsenstein M, Paderova J, Hsien J, Squire JA, Higgins MJ, Nagy A, Lefebvre L. (2007) Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7. Mol Cell Biol. 2007 Nov 26; [Epub ahead of print]
152. Peerani R, Rao BM, Bauwens C, Yin T, Wood GA, Nagy A, Kumacheva E, Zandstra PW. (2007) Niche-mediated control of human embryonic stem cell self-renewal and differentiation.EMBO J. 2007 Oct 18; [Epub ahead of print]
151. MacAulay K, Doble BW, Patel S, Hansotia T, Sinclair EM, Drucker DJ, Nagy A, Woodgett JR. (2007) Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism. Cell Metab. 2007 Oct;6(4):329-37.
150. Sunyoung Lee, Tom T. Chen, Chad L. Barber, Maria C. Jordan, Jared Murdock, Sharina Desai, Napoleone Ferrara, Andras Nagy, Kenneth P. Roos, and M. Luisa Iruela-Arispe (2007) Autocrine VEGF Signaling Is Required for Vascular Homeostasis. Cell, Vol 130, 691-703.
149. The International Stem Cell Initiative*, Adewumi O, Aflatoonian B, Ahrlund-Richter L, Amit M, Andrews PW, Beighton G, Bello PA, Benvenisty N, Berry LS, Bevan S, Blum B, Brooking J, Chen KG, Choo AB, Churchill GA, Corbel M, Damjanov I, Draper JS, Dvorak P, Emanuelsson K, Fleck RA, Ford A, Gertow K, Gertsenstein M, Gokhale PJ, Hamilton RS, Hampl A, Healy LE, Hovatta O, Hyllner J, Imreh MP, Itskovitz-Eldor J, Jackson J, Johnson JL, Jones M, Kee K, King BL, Knowles BB, Lako M, Lebrin F, Mallon BS, Manning D, Mayshar Y, McKay RD, Michalska AE, Mikkola M, Mileikovsky M, Minger SL, Moore HD, Mummery CL, Nagy A, Nakatsuji N, O'brien CM, Oh SK, Olsson C, Otonkoski T, Park KY, Passier R, Patel H, Patel M, Pedersen R, Pera MF, Piekarczyk MS, Pera RA, Reubinoff BE, Robins AJ, Rossant J, Rugg-Gunn P, Schulz TC, Semb H, Sherrer ES, Siemen H, Stacey GN, Stojkovic M, Suemori H, Szatkiewicz J, Turetsky T, Tuuri T, van den Brink S, Vintersten K, Vuoristo S, Ward D, Weaver TA, Young LA, Zhang W. (2007) Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol. 2007 Jun 17; [Epub ahead of print] PMID: 17572666 [PubMed - as supplied by publisher]
148. Sophia H. L. George, Marina Gertsenstein, Kristina Vintersten, Ella Korets-Smith, John Murphy, Mary E. Stevens, Jody J. Haigh, and Andras Nagy (2007) Developmental and adult phenotyping directly from mutant embryonic stem cells. PNAS published March 2, 2007, 10.1073/pnas.0609277104
147. Cervi D, Shaked Y, Haeri M, Usenko T, Lee CR, Haigh JJ, Nagy A, Kerbel RS, Yefenof E, Ben-David Y. (2007) Enhanced natural-killer cell and erythropoietic activities in VEGF-A-overexpressing mice delay F-MuLV-induced erythroleukemia. Blood. 2007 Mar 1;109(5):2139-46. Epub 2006 Oct 19
146. The International Mouse Knockout Consortium (2007) A mouse for all reason. Cell 128, January 12, 2007: 9-13.
145. Draper JS, Nagy A. (2006) Improved embryonic stem cell technologies. Handb Exp Pharmacol. 2007;178:107-28. PMID: 17203653
144. Nagy A, Vintersten K. (2006) Murine embryonic stem cells. Methods Enzymol. 2006;418:3-21. PMID: 17141026
143. Takeda K, Ho V, Takeda H, Duan LJ, Nagy A, Fong GH. (2006) Placental but not Heart Defect Is Associated with Elevated HIF{alpha} Levels in Mice Lacking Prolyl Hydroxylase Domain Protein 2. Mol Cell Biol. 2006 Sep 11; [Epub ahead of print]
142. Amano T, Gertsenstein M, Nagy A, Kurihara H, Suzuki H. (2006) Nuclear transfer reprogramming does not improve the low developmental potency of embryonic stem cells induced by long-term culture. Reproduction. 2006 Aug;132(2):257-63.
141. Wada T, Haigh JJ, Ema M, Hitoshi S, Chaddah R, Rossant J, Nagy A, van der Kooy D. (2006) Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival. J Neurosci. 2006 Jun 21;26(25):6803-12.
140. Eremina V, Cui S, Gerber H, Ferrara N, Haigh J, Nagy A, Ema M, Rossant J, Jothy S, Miner JH, Quaggin SE. (2006) Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival. J Am Soc Nephrol. 2006 Mar;17(3):724-35. Epub 2006 Jan 25.
139. Nagy A. (2005) Following Ariadne's thread in the labyrinth of mouse phenotypes. Development. 2005 Dec;132(23):5130-2.
138. Chen J, Reifsnyder PC, Scheuplein F, Schott WH, Mileikovsky M, Soodeen-Karamath S, Nagy A, Dosch MH, Ellis J, Koch-Nolte F, Leiter EH. (2005) "Agouti NOD": identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells. Mamm Genome. 2005 Oct;16(10):775-783. Epub 2005 Oct 29.
137.
Bubnic SJ, Nagy A, Keating A. (2005) Donor hematopoietic cells
from transgenic mice that express GFP are immunogenic in immunocompetent
recipients.
Hematology.
2005 Aug;10(4):289-95.
136. Schnabel D, Ramirez L, Gertsenstein M, Nagy A, Lomeli H.(2005) Ectopic expression of KitD814Y in spermatids of transgenic mice, interferes with sperm morphogenesis. Dev Dyn. 233(1):29-40.
135. Jun K. Takeuchi, Maria Mileikovskaia, Kazuko Koshiba-Takeuchi, Analeah B. Heidt, Alessandro D. Mori, Eric P. Arruda, Marina Gertsenstein, Romain Georges, Lorinda Davidson, Rong Mo, Chi-chung Hui, R. Mark Henkelman, Mona Nemer, Brian L. Black, Andras Nagy and Benoit G. Bruneau (2005) Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development Development. 132(10):2463-74. Epub 2005 Apr 20.
134. Gusztav Belteki, Jody Haigh, Nikolett Kabacs, Katharina Haigh, Karen Sison, Frank Costantini, Jeff Whitsett, Susan E. Quaggin and Andras Nagy (2005) Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction. Nucleic Acids Research 2005 33(5):e51; doi:10.1093/nar/gni051
133. Monteggia LM, Barrot M, Powell CM, Berton O, Galanis V, Gemelli T, Meuth S, Nagy A, Greene RW, Nestler EJ. (2004) Essential role of brain-derived neurotrophic factor in adult hippocampal function. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10827-32. Epub 2004 Jul 12. PMID: 15249684
132. Quaggin S. E., Chan, A and Nagy, A (2004) Genetic manipulation of mice to study cardiovascular disease. Drug Discovery Today: Disease Models Volume 1, Issue 3, 243-248
131.Vintersten K, Monetti C, Gertsenstein M, Zhang P, Laszlo L, Biechele S, Nagy A.(2004) Mouse in red: Red fluorescent protein expression in mouse ES cells, embryos, and adult animals. genesis. 2004 Dec 9;40(4):241-246
130. Ramos-Mejia V, Escalante-Alcalde D, Kunath T, Ramirez L, Gertsenstein M, Nagy A, Lomeli H. (2004) Phenotypic analyses of mouse embryos with ubiquitous expression of Oct4: Effects on mid-hindbrain patterning and gene expression. Dev Dyn. 2004 Dec 3;232(1):180-190
129. Schwarz Q, Gu C, Fujisawa H, Sabelko K, Gertsenstein M, Nagy A, Taniguchi M, Kolodkin AL, Ginty DD, Shima DT, Ruhrberg C.(2004) Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve.Genes Dev. 2004 Nov 15;18(22):2822-34.
128. Kehler J, Tolkunova E, Koschorz B, Pesce M, Gentile L, Boiani M, Lomeli H, Nagy A, McLaughlin KJ, Scholer HR, Tomilin A. (2004) Oct4 is required for primordial germ cell survival. EMBO Rep. 2004 Nov;5(11):1078-83.
127. Korets-Smith E, Lindemann L, Tucker KL, Jiang C, Kabacs N, Belteki G, Haigh J, Gertsenstein M, Nagy A. (2004) Cre recombinase specificity defined by the tau locus.genesis. 2004 Nov;40(3):131-8.
126. Bäckhed, F., Ding, H., Wang, T., Hooper, L. V., Koh, G. Y., Nagy, A., Semenkovich, CF., Gordon, J. I. (2004) The gut microbiota as an environmental factor that regulates fat storage. Proc. Natl. Acad. Sci. U S A. 2004 Nov 2;101(44):15718-23.
125. Haigh JJ and Nagy A (2004) Whole Mount Analysis of the Embryonic Vasculature. Methods in Endothelial Cell Biology. Series : Springer Lab Manuals Augustin, Hellmut G. (Ed.) p. 325-336.
124. Ding H, Wu X, Bostrom H, Kim I, Wong N, Tsoi B, O'Rourke M, Koh GY, Soriano P, Betsholtz C, Hart TC, Marazita ML, Field LL, Tam PP, Nagy A. (2004) A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling. Nature Genetics 2004 Oct;36(10):1111-6. Sep 7 Epub 2004 Sep 07
123. Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH, Lloyd KC, Magnuson T, Moore MW, Nagy A, Pollock JD, Roses AD, Sands AT, Seed B, Skarnes WC, Snoddy J, Soriano P, Stewart DJ, Stewart F, Stillman B, Varmus H, Varticovski L, Verma IM, Vogt TF, von Melchner H, Witkowski J, Woychik RP, Wurst W, Yancopoulos GD, Young SG, Zambrowicz B.(2004) The knockout mouse project. Nature Genetics 36: 921 - 924
122. Hao Ding, Mike Schertzer, Xiaoli Wu, Marina Gertsenstein, Sara Selig, Makoto Kammori, Reza Pourvali, Steven Poon, Irma Vulto, Elizabeth Chavez, Patrick P.L. Tam, Andras Nagy, and Peter M. Lansdorp (2004). Regulation of Murine Telomere Length by Rtel: An Essential Gene Encoding a Helicase-like Protein. Cell Vol 117, 873-886, 25 June 2004
121. Nordal RA, Nagy A, Pintilie M, Wong CS.(2004) Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: a role for vascular endothelial growth factor. Clin Cancer Res. 2004 May 15;10(10):3342-3353.
120. Haigh JJ, Ema M, Haigh K, Gertsenstein M, Greer P, Rossant J, Nagy A, Wagner EF. (2004) Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells. Blood 2004 Feb 1;103(3):912-920.
119. Martin R, Lahlil R, Damert A, Miquerol L, Nagy A, Keller G, Hoang T. (2004) SCL interacts with VEGF to suppress apoptosis at the onset of hematopoiesis. Development. 2004 Feb;131(3):693-702.
118. Duan LJ, Nagy A, Fong GH. (2003) Gastrulation and angiogenesis, not endothelial specification, is sensitive to partial deficiency in vascular endothelial growth factor-a in mice. Biol Reprod. 2003 Dec;69(6):1852-8.
117. Viswanathan S, Benatar T, Mileikovsky M, Lauffenburger DA, Nagy A, Zandstra PW. (2003) Supplementation-dependent differences in the rates of embryonic stem cell self-renewal, differentiation, and apoptosis. Biotechnol Bioeng. 84(5):505-17
116. Haigh JJ, Gerhardt H, Morelli P, Haigh K, Tsien J, Damert A, Miquerol L, Muhlner U, Klein R, Ferrara N, Wagner EF, Betsholtz C, and Nagy A (2003) Cortical and retinal defects caused by dosage dependent reductions in VEGF-A. Dev. Biol. 262: 225-241
115. Viloria-Petit A, Miquerol L, Yu JL, Gertsenstein M, Sheehan C, May L, Henkin J, Lobe C, Nagy A, Kerbel RS, Rak J. (2003) Contrasting effects of VEGF gene disruption in embryonic stem cell-derived versus oncogene-induced tumors. EMBO J. 2003 Aug 15;22(16):4091-102.
114. Metzler M, Li B, Gan L, Georgiou J, Gutekunst C-A, Wang Y, Torre E, Devon RS, Oh R, Legendre-Guillemin V, Rich M, Alvarez C, Gertsenstein M, McPherson PS, Nagy A, Wang YT, Roder JC, Raymond LA and Hayden MR (2003) Disruption of the Endocytic Protein HIP1 Results in Neurological Deficits and Decreased AMPA Receptor Trafficking. EMBO J. 2003 Jul 1;22(13):3254-66.
113. Fitzpatrick LA, Buzas E, Gagne TJ, Nagy A, Horvath C, Ferencz V, Mester A, Kari B, Ruan M, Falus A, Barsony J. (2003) Targeted deletion of histidine decarboxylase gene in mice increases bone formation and protects against ovariectomy-induced bone loss. Proc Natl Acad Sci U S A. 2003 Apr 25
112. Hunyady B, Zolyomi A, Czimmer J, Mozsik G, Kozicz T, Buzas E, Tanaka S, Ichikawa A, Nagy A, Palkovits M, Falus A. (2003) Expanded parietal cell pool in transgenic mice unable to synthesize histamine. Scand J Gastroenterol. 2003 Feb;38(2):13
111. Apicelli AJ, Uhlmann EJ, Baldwin RL, Ding H, Nagy A, Guha A, Gutmann DH. (2003) Role of the Rap1 GTPase in astrocyte growth regulation. Glia. May;42(3):225-3
110. Kimura T, Suzuki A, Fujita Y, Yomogida K, Lomeli H, Asada N, Ikeuchi M, Nagy A, Mak TW, Nakano T. (2003) Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production. Development 130(8):1691-1700
109. Ding H, Shannon P, Lau N, Wu X, Roncari L, Baldwin RL, Takebayashi H, Nagy A, Gutmann DH, Guha A. (2003) Oligodendrogliomas Result from the Expression of an Activated Mutant Epidermal Growth Factor Receptor in a RAS Transgenic Mouse Astrocytoma Model. Cancer Res. 63(5):1106-13.
108. Eremina V, Sood M, Haigh J, Nagy A, Lajoie G, Ferrara N, Gerber HP, Kikkawa Y, Miner JH, Quaggin SE. (2003) Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest 111(5):707-716
107. Mezey
E, Nagy A, Szalayova I, Key S, Bratincsak A, Baffi J, Shahar T. (2003)
Comment on "Failure of bone marrow cells to transdifferentiate into
neural cells in vivo".
Science 299(5610):1184
106. Nagy, A., Perrimon, N., Sandmeyer, S. and Plasterk, R. (2003) Tailoring the genome; the power of genetic approaches. Nature Genetics Mar;33 Suppl:276-84
105. Belteki, G., David W. Ow, D.W. and Nagy, A. (2003) Site-specific cassette exchange and germline transmission with mouse ES cells expressing PhiC31 integrase. Nature Biotechnology Mar;21(3):321-4.
104. Lau N, Uhlmann EJ, Von Lintig FC, Nagy A, Boss GR, Gutmann DH, Guha A.(2003) Rap1 activity is elevated in malignant astrocytomas independent of tuberous sclerosis complex-2 gene expression. Int J Oncol. 22(1):195-200.
103. Nagy A., Gertsensten M., Vintersten K. and Behringer R. (2003) Manipulating the Mouse Embryo; A Laboratory manual. 3rd edition, Cold Spring Harbor Press, Cold Spring Harbor, New York
102. Behrens A, Haigh J, Mechta-Grigoriou F, Nagy A, Yaniv M, Wagner EF. (2003) Impaired intervertebral disc formation in the absence of Jun. Development. 130(1):103-109.
101. Maatman R, Gertsenstein M, de Meijer E, Nagy A, Vintersten K. (2003) Aggregation of embryos and embryonic stem cells. Methods Mol Biol. 209:201-30.
100. Radomska HS, Gonzalez DA, Okuno Y, Iwasaki H, Nagy A, Akashi K, Tenen DG, Huettner CS. (2002) Transgenic targeting with regulatory elements of the human CD34 gene. Blood. 2002 Aug 15 [epub ahead of print]
99. Pap E, Racz K, Kovacs JK, Varga I, Buza E, Madarasz B, Foldes C, Szalai C, Watanabe T, Ohtsu H, Ichikawa A, Nagy A, Falus A. (2002) Histidine decarboxylase deficiency in gene knockout mice elevates male sex steroid production. J Endocrinol 175(1):193-199.
98.
Makabe-Kobayashi Y, Hori Y, Adachi T, Ishigaki-Suzuki S, Kikuchi Y, Kagaya
Y, Shirato K, Nagy A, Ujike A, Takai T, Watanabe T, Ohtsu H. (2002) The
control effect of histamine on body temperature and respiratory function
in IgE-dependent systemic anaphylaxis.
J
Allergy Clin Immunol. 10(2):298-303.
97. Hori Y, Nihei Y, Kurokawa Y, Kuramasu A, Makabe-Kobayashi Y, Terui T, Doi H, Satomi S, Sakurai E, Nagy A, Watanabe T, Ohtsu H. (2002) Accelerated clearance of Escherichia coli in experimental peritonitis of histamine-deficient mice. J Immunol. 169(4):1978-83.
96. Perl AK, Wert SE, Nagy A, Lobe CG, Whitsett JA. (2002) Early restriction of peripheral and proximal cell lineages during formation of the lung. Proc Natl Acad Sci U S A. 99(16):10482-7.
95. Ohtsu H, Kuramasu A, Tanaka S, Terui T, Hirasawa N, Hara M, Makabe-Kobayashi Y, Yamada N, Yanai K, Sakurai E, Okada M, Ohuchi K, Ichikawa A, Nagy A, Watanabe T. (2002) Plasma extravasation induced by dietary supplemented histamine in histamine-free mice. Eur J Immunol.32(6):1698-708.
94. Logan, M,, Martin, J.M., Nagy, A., Lobe, C., Olson, E.n. and Tabin C.J. (2002) Expression of Cre Recombinase in the Developing Mouse Limb Bud Driven by a PrxI Enhancer. genesis 33: 77-80.
93. Hadjantonakis, A.-K., Macmaster, S. and Nagy, A. (2002) Embryonic stem cells and mice expressing different GFP variants for multiple non-invasive reporter usage within a single animal. BMC Biotechnology 2002 2: 11
92. Bayle JH, Randazzo F, Johnen G, Kaufman S, Nagy A, Rossant J, Crabtree G.(2002) Hyperphenylalaninemia and impaired glucose tolerance in mice lacking the bifunctional DCoH gene. J Biol Chem 2002 May 13; [epub ahead of print]
91. Chan EY, Nasir J, Gutekunst CA, Coleman S, Maclean A, Maas A, Metzler M, Gertsenstein M, Ross CA, Nagy A, Hayden MR.(2002) Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior. Hum Mol Genet 11(8):945-959
90. Wiener, Z., Andrásfalvy, M., Pállinger, E., Kovács, P., Szalai, Cs., Erdei, A., Tóth, S., Nagy, A. and Falus, A.(2002) Bone marrow-derived mast cell differentiation is strongly reduced in histidine decarboxylase knockout, histamine-free mice. International Immunology, 14: 381-387.
89. Damert, A., Lucile Miquerol, L., Gertsenstein, M., Risau, W. and Nagy, A. 2002. Insufficient VEGF-A activity in yolk sac endoderm compromises haematopoietic and endothelial differentiation. Development 129(8):1881-1892.
88. Ding, H., Wu, X. and Nagy, A. (2002) Mice with Cre recombinase activatable PDGF-C expression. genesis 32(2): 181-183.
87. Horváth, B. V., Falus, A., Tóth, S., Szalai, Cs., Lázár-Molnár, E., Holub, M. Cs., Buzás, E., Nagy, A. and Fulop, A. K. (2002) Inverse regulation of interleukin-6 (IL-6) and IL-6 receptor in histamine deficient histidine decarboxylase-knock-out mice. Immunology Letters 80(3):151-154.
86. Tanaka, S., Hamada, K., Yamada, N., Sugita, Y., Tonai, S. Hunyadi, B., Palkovits, M., Falus, A., Watanabe, T., Okabe, S., Ohtsu, H., Ichikawa, A. and Nagy, A. (2002) Gastric acid secretion in L-histidine decarboxylase deficient mice. Gastroenterology 122(1):145-155.
85. Gertsenstein, M., Lobe, C. and Nagy, A. (2002) ES cell mediated conditional transgenesis. In Embryonic Stem Cells: Methods and Protocols Edited by Kursad Turksen, Humana Press's Methods in Molecular Biology 185:285-307
84. Kinder, S. J., Tsang, T. E., Wakamiya, M., Sasaki, H., Behringer, R. R., Nagy, A and Tam P. P. L. (2001) The organizer of the mouse gastrula is composed of a dynamic population of progenitor cells for the axial mesoderm. Development 128: 3623-3634.
83. Ohtsu H, Tanaka S, Terui T, Hori Y, Makabe-Kobayashi Y, Pejler G, Tchougounova E, Hellman L, Gertsenstein M, Hirasawa N, Sakurai E, Buzas E, Kovacs P, Csaba G, Kittel A, Okada M, Hara M, Mar L, Numayama-Tsuruta K, Ishigaki-Suzuki S, Ohuchi K, Ichikawa A, Falus A, Watanabe T, Nagy A. (2001) Mice lacking histidine decarboxylase exhibit abnormal mast cells. FEBS Lett. 502(1-2): 53-56.
82. Wang, J., Mager, J., Chen, Y., Schneider, E., Cross, J.C., Nagy, A. and Magnuson, T. (2001) Imprinted X inactivation maintained by a mouse Polycomb group gene. Nature Genetics 28: 371-375.
81. Hegyi K, Fulop AK, Toth S, Buzas E, Watanabe T, Ohtsu H, Ichikawa A, Nagy A, Falus A. (2001) Histamine deficiency suppresses murine haptoglobin production and modifies hepatic protein tyrosine phosphorylation. Cell. Mol. Life Sci. 58: 850–854.
80. Csankovszki, Gy., Nagy, A. and Jaenisch R. (2001) Synergism of Xist RNA, DNA Methylation, and Histone Hypoacetylation in Maintaining X Chromosome Inactivation. The Journal of Cell Biology, 153(4): 773–783.
79. Zandstra, PW., Nagy, A. (2001) Stem Cell Bioengeneering. Annual review of biomedical engineering.3:275-305.
78. Ding, H., Roncari, L., Shannon, P., Wu, X., Lau, N., Karaskova, J., Gutmann, D. H., Squire, J. A., Nagy, A. and Guha, A. (2001) Astrocyte-specific Expression of Activated p21-ras Results in Malignant Astrocytoma Formation in a Transgenic Mouse Model of Human Gliomas. Cancer Research 6: 3826–3836.
77. Nagy, A. and Rossant, J. (2001) Chimaeras and mosaics for dissecting complex mutant phenotypes Int. J. Dev. Biol. 45: 577-582.
76. Yu, JL., Rak, JW., Carmeliet, P., Nagy, A., Kerbel, RS., Coomber, BL. (2001) Heterogeneous Vascular Dependence of Tumor Cell Populations. Am J Pathol. Apr;158(4):1325-1334.
75. Pinter, E., Haigh, J., Nagy, A., Madri, JA. (2001) Hyperglycemia-Induced Vasculopathy in the Murine Conceptus Is Mediated via Reductions of VEGF-A Expression and VEGF Receptor Activation. Am J Pathol. Apr;158(4):1199-1206.
74. Hadjantonakis, A.-K., Cox, L. L., 2,5, Tam, P. P. L. and Nagy, A. (2001) An X-linked GFP transgene reveals unexpected paternal X-chromosome activity in trophoblastic giant cells of the mouse placenta. genesis 29: 133-140.
73. Lefebvre, L., Dionne, N., Karaskova, J., Squire, J. A. and Nagy, A. (2001) Selection for transgene homozygosity in ES cells results in extensive loss of heterozygosity. Nature Genetics 27: 257-258.
72. Hadjantonakis, A.-K. and Nagy, A. (2001) The color of mice: in the light of GFP-variant reporters. Histochemistry and Cell Biology 115: 49-58.
71. Nagy, A. and Mar, L. (2001) Creation and Use of a Cre Recombinase Transgenic Database. In Methods in Molecular Biology, vol. 158:95-106.: Gene Knockout Protocols Edited by: M. J. Tymms and I. Kola © Humana Press Inc., Totowa, NJ
70. Tanaka, M., Hadjantonakis A.-K., and Nagy, A. (2001) Combining ES Cells and Diploid and Tetraploid Embryos. In Methods in Molecular Biology, vol. 158:135-54: Gene Knockout Protocols Edited by: M. J. Tymms and I. Kola © Humana Press Inc., Totowa, NJ
69. Hemberger, M., Kurz, H., Orth, A., Otto, S., Luttges, A., Elliott, R., Nagy, A., Tan, S-S., Tam, P., Zechner, U., Fundele, R.H. (2001) Genetic and Developmental Analysis of X-Inactivation Hybrid Mice Suggests a Role for the Y Chromosome in Placental Dysplasia. Genetics 157: 341-348.
68. Ding, H., Roncari, L., Wu, X., Lau, N., Shannon, P., Nagy, A. and Guha, A. (2001) Expression and Hypoxic Regulation of Angiopoietins in Human Astrocytomas. Neurooncology, 3(1): 1-10.
67. Adelman, D.M., Gertsenstein, M., Nagy, A., M. Simon, C, and Maltepe, E. (2000) Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses. Genes and Development 14: 3191-3203.
66. Pennisi, D., Bowles, J., Nagy, A., Muscat, G. and Koopman, P. (2000) Mice null for Sox18 are viable and display a mild coat defect. Molecular and Cellular Biology 20: 9331-9336.
65. Novak, A., Guo, C., Yang, W., Nagy, A. and Lobe, C. L. (2000) Z/EG, a double reporter mouse line that expresses Enhanced Green Fluorescent Protein upon Cre-mediated excision. genesis 28: 147-155.
64. Ding, H., Wu, X., Roncari, L., Lau, N., Shannon, P., Nagy, A. and Guha, A. (2000) Expression and regulation of Neuropilin-1 in human astrocytomas. International Journal of Cancer 88: 584-592.
63. Ding, H., Wu, X., Kim, I., Tam, P.P.L., Koh , G.Y and Nagy, A. (2000) The mouse Pdgfc gene: dynamic expression in embryonic tissues during organogenesis. Mech. Dev. 96(2): 209-213.
62. Miquerol, L., Langille, B. L. and Nagy, A. (2000) Embryonic Development is Disrupted by Modest Increases in Vascular Endothelial Growth Factor Gene Expression. Development 127(18): 3941-3946.
61. Hadjantonakis, A.-K. and Nagy, A. (2000) Use of FACS for the isolation of individual cells from transgenic mice harboring a GFP reporter. genesis 27: 95-98.
60. Hardouin, N. and Nagy, A. (2000) Gene-trap based target site for Cre-mediated transgenic insertion. genesis 26(4): 245-252.
59. Hardouin, N. and Nagy, A. (2000) Mini review: Mouse models for human disease. Clinical Genetics 57:237-244.
58. Nagy, A. (2000) Cre recombinase: the universal reagent for genome tailoring. genesis 26(2): 99-109.
57. Lomelí, H., V. Ramos-Mejía, M. Gertsenstein, C.G. Lobe and A. Nagy (2000) Targeted insertion of Cre recombinase into the TNAP gene: excision in primordial germ cells. genesis 26(2): 116-117.
56. Nagy, A. and J. Rossant (1999). Production and analysis of ES-cell aggregation chimeras. In Gene Targeting: A Practical Approach (ed. A. Joyner, Second Edition), Oxford University Press Inc., New York, pp. 177-206.
55. Kinder, S.J., T.E. Tsang, G.A. Quinlan, A-K. Hadjantonakis, A. Nagy and P.Tam (1999) The orderly allocation of mesodermal cells to the extraembryonic structures and the anterior-posterior axis during gastrulation of the mouse embryo. Development, 126(21):4691-4701.
54. Zhang, J., A. Shehabeldin, L.A. G. da Cruz, J. Butler, A-K Somani, M. McGavin, I. Kozieradzki, A. O. dos Santos, A. Nagy, S. Grinstein, J. M. Penninger, K. A. Siminovitch (1999). Antigen Receptor-induced Activation and Cytoskeletal Rearrangement are Impared in Wiskott-Aldrich Syndrome Protein-deficient Lymphocytes. J. Exp. Med. 190 (9): 1-13.
53. Tanaka, M., M. Puchyr, M. Gertsenstein, K. Harpal, R. Jaenisch, J. Rossant and A. Nagy (1999). Parental origin-specific expression of Mash2 is established at the time of implantation with its imprinting mechanism highly resistant to genome-wide demethylation. Mech Dev Sep 1; 87(1-2): 129-142.
52. Miquerol, L., M. Gertsenstein, K. Harpal, J.Rossant and A. Nagy (1999). Multiple developmental roles of VEGF suggested by a LacZ-tagged allele. Dev Biol Aug 15; 212(2): 307-322.
51. Carmeliet, P., Y-S. Ng, D. Nuyens, G. Theilmeier, K. Brusselmans, I. Cornelissen, E. Ehler, V. V. Kakkar, I. Stalmans, V. Mattot, J-C. Perriard, M. Dewerchin, W. Flameng, A. Nagy, F. Lupu, L. Moons, D. Collen, P. A. D'Amore & D. T. Shima (1999). Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188 Nat Medicine 5(5): 495 - 502.
50. Lobe C.G., Koop, K.E., Kreppner, W., Lomeli, H., Gertsenstein, M., Nagy, A. (1999). Z/AP, a Double Reporter for Cre-Mediated Recombination. Dev Biol. Apr 15; 208(2):281-292.
49.Nozaki M., Ohishi K., Yamada N., Kinoshita T., Nagy A., Takeda J. (1999) Developmental abnormalities of glycosylphosphatidylinositol-anchor-deficient embryos revealed by Cre/loxP system. Lab Invest Mar;79(3):293-299.
48. Rossant, J. and Nagy, A. (1999) In search of the tabula rasa of human cells. Nat Biotechnol. Jan;17(1):23-24. No abstract available.
47. Tanaka S, T. Kunath, A-K. Hadjantonakis, A. Nagy, J. Rossant (1998). Promotion of trophoblast stem cell proliferation by FGF4. Science 282(5396), 2072-2075.
46. Hadjantonakis, A.-K., M. Pirity and A. Nagy (1998). Cre recombinase mediated alterations of the mouse genome for the study of embryonic development. In Methods in Molecular Bilogy, Vertebrate Embryology (eds. P.T. Sharpe and I.J. Mason) 97: 101-122.
45. Hadjantonakis, A-K., M. Gertsenstein, M. Ikawa, M. Okabe and A. Nagy (1998). Generation of green fluorescent mice by germline transmission of green flourescent ES cells. Mech Dev. 76, 79-90.
44. Hadjantonakis, A-K., M. Gertsenstein, M. Ikawa, M. Okabe and A. Nagy (1998). Non-invasive sexing of preimplantation stage mammalian embryos. Nat Genet. 19(3), 220-222.
43. Pirity, M., A.-K. Hadjantonakis and A. Nagy (1998). Embryonal stem cells, creating transgenic animals. In Methods Cell Biol . (eds. J.P. Mather and D. Barnes). Academic Press, San Diego 57, 279-293 .
42. Rossant, J., F. Guillemot, M. Tanaka, K. Latham, M. Gertsenstein and A. Nagy (1998). Mash2 is expressed in oogenesis and preimplantation development but is not required for blastocyst formation. Mech Dev. 73(2), 183-191.
41. Nagy, A., C. Moens, E. Ivanyi, J. Pawling, M. Gertsenstein K. Hadjantonakis, M. Pirity and J. Rossant (1998). Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles. Current Biology 8, 661-664.
40. Lobe, C.G. and A. Nagy (1998). Conditional genome alteration in mice. BioEssays 20, 200-208.
39. Tanaka, M., M. Gertsenstein, J. Rossant and A. Nagy (1997). Mash2 acts cell autonomously in mouse spongiotrophoblast development. Dev. Biol. 190, 55-65.
38. Carmeliet, P., L. Moons, M. Dewerchin, N. Mackman, T. Luther, G. Breier, V. Ploplis, M. Muller, A. Nagy, E. Plow, R. Gerard, T. Edgington, W. Risau and D. Collen (1997). Insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the plasminogen system. Ann. N. Y. Acad. Sci. 811, 191-206.
37. Nagy, A. (1997). Formation of mouse chimeric embryos from ES cells. In Transgenic Animals: Generation and Use (ed. L.-M. Houdebine), Harwood Academic Publishers, Amsterdam, pp. 167-172.
36. Duncan, S.A., A. Nagy, and W. Chan (1997). Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4-/- embryos. Development 124, 279-287.
35. Nagy, A. (1996). Engineering the mouse genome. In Mammalian Development (ed. P. Lonai), Harwood Academic Publishers, Amsterdam, pp. 339-371.
34. Carmeliet, P., V. Ferreira, G. Breier, S. Pollefeyt, L. Kieckens, M. Gertsenstein, M. Fahrig, A. Vandenhoeck, K. Harpal, C. Eberhardt, C. Declerq, J. Pawling, L. Moons, D. Collen, W. Risau and A. Nagy (1996). Abnormal blood vessel development and lethality in embryos lacking a single vascular endothelial growth factor allele. Nature 380, 435-439.
33. Nagy, A. and J. Rossant (1996). Targeted mutagenesis: analysis of phenotype without germ line transmission. J. Clin. Invest. 97, 1360-1365.
32. Forrester, L., A. Nagy, M. Sam, A. Watt, L. Stevenson, A. Bernstein, A.L. Joyner and W. Wurst (1996). An induction gene trap screen in embryonic stem cells: identification of genes that respond to retinoic acid in vitro. Proc. Natl. Acad. Sci. USA 93, 1677-1682.
31. Rossant, J. and A. Nagy (1995). Genome engineering: the new mouse genetics. Nat. Med. 1, 592-594.
30. Guillemot, F., T. Caspary, S.M. Tilghman, N.G. Copeland, D.J. Gilbert, N.A. Jenkins, D.J. Anderson, A.L. Joyner, J. Rossant and A. Nagy (1995). Genomic imprinting of Mash-2, a mouse gene required for trophoblast development. Nat. Genet. 9, 235-241.
29. Guillemot, F., A. Nagy, A. Auerbach, J. Rossant and A.L. Joyner (1994). Essential role of Mash-2 in extraembryonic development. Nature 371, 333-336.
28. Chambers, C., J. Kang, J. Pawling, B. Huber, N. Hozumi and A. Nagy (1994). Exogenous Mtv-7 superantigen expression in major histocompatibility complex class II I-E- mice reconstituted with embryonic stem cell-derived hematopoietic stem cells. Proc. Natl. Acad. Sci. USA 91, 1138-1142.
27. Nagy, A. and J. Rossant (1993). Production of completely ES-cell derived fetuses. In Gene Targeting: A Practical Approach (ed. A. Joyner), Oxford University Press Inc., New York, pp. 147-179.
26. Wood, S.A., N.D. Allen, J. Rossant, A. Auerbach and A. Nagy (1993). Non-injection methods for the production of embryonic stem cell-embryo chimaeras. Nature, 365, 87-89.
25. Nagy, A., J. Rossant, R. Nagy, W. Abramow-Newerly and J.C. Roder (1993). Derivation of completely cell culture-derived mice from early passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90, 8424-8428.
24. Rossant, J., C.B. Moens and A. Nagy (1993). Genome manipulation in embryonic stem cells. In Transgenic Modification of Germline and Somatic Cells (ed. R.B. Flawell and R.B. Heap), Chapman and Hall, London, pp. 69-77.
23. Rossant, J., C.B. Moens and A. Nagy (1993). Genome manipulation in embryonic stem cells. Phil. Trans. R. Soc. Lond. B 339, 207-215.
22. Rossant, J., E. Merentes-Diaz, E. Gocza, E. Ivanyi and A. Nagy (1991). Developmental potential of mouse embryonic stem cells. In Serono Symposium on Preimplantation Embryo Development (ed. B.D. Bavister), Springler-Verlag, N.Y., pp. 157-165.
21. Forrester, L.M., A. Bernstein, J. Rossant and A. Nagy (1991). Long-term reconstitution of the mouse hematopoietic system by embryonic stem cell-derived fetal liver. Proc. Natl. Acad. Sci. USA 88, 7514-7517.
20. Nagy, A., E. Gocza, E. Merentes-Diaz, V.R. Prideaux, E. Ivanyi, M. Markkula and J. Rossant (1990). Embryonic stem cells alone are able to support fetal development in the mouse. Development 110, 815-821.
19. Nagy, A., M. Markkula and M. Sass (1989). Systematic non-uniform distribution of parthenogenetic cells in adult mouse chimeras. Development 106, 321-324.
18. Paldi, A., A. Nagy, M. Markkula, I. Barna and L. Dezso (1989). Postnatal development of parthenogenetic-fertilized mouse aggregation chimeras. Development 105, 115-118.
17. Nagy, A., A. Paldi, L. Dezso, L. Varga and A. Magyar (1987). Prenatal fate of parthenogenetic cells in mouse aggregation chimeras. Development 101, 67-71.