Lunenfeld-Tanenbaum Research Institute

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Culotti Lab



 2013 | 2012 |2010|20092007 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 |



Daple, G., Zheng, H., Brown, L., Culotti, J. (2012) Semaphorin-1 and netrin signal in parallel and permissively to position the male ray 1 sensillum in Caenorhabditis elegans. Genetics. 2012 Nov;192(3):959-71.

Ikegami, R., Simokat, K., Zheng, H., Brown, L., Garriga, G., Hardin, J., Culotti, J. (2012) Semaphorin and Eph receptor signaling guide a series of cell movements for ventral enclosure in C. elegans. Current Biology. 10;22(1):1-11



Souza, RP, Romano-Silva,MA, Lieberman, JA, Meltzer, HY, MacNeil, LT, Culotti, JG, Kennedy, JL, Wong, AHC. (2010) Genetic association of the GDNF alpha-receptor genes with schizophrenia and clozapine response. J. Psych. Res. Aug; 44(11):700-6.

Jafari, G., Burghoorn, J., Kavano, T., Mathew, M., Morck, C, Axang, C., Ailion, M., Thomas, JH, Culotti, JG, Swoboda, P., and Pilon, M. (2010). Genetics of extracellular matrix remodelling during organ growth using the C. elegans pharynx model. Genetics. Nov;186(3):969-82.



Suo, S., Culotti, J.G., and Van Tol, H.H.M. (2009) Dopamine counteracts octopamine signaling in a neural circuit mediating food response in C. elegans.  EMBO J. 28: 2437-2448.

Kawano, T., Zheng, H., Merz, D.C., Kohara, Y., Tamai, K.K., Nishiwaki, K., and Culotti, J.G. (2009). C. elegans mig-6/ppn-1 Encodes Papilin Isoforms Affecting Distinct Aspects of DTC Migration and Interacts Genetically with mig-17 and collagen IV. Development. May: 136(9): 1433-1442.

MacNeil, L., Hardy, W.R., Pawson, T., Wrana, J.L., and Culotti, J.G. (2009) Unc-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways. Nature Neuroscience. Feb: 12(2): 150-155.

Suo, S., Culotti, J.G., and Van Tol, H.H.M. (2009) Dopamine suppresses octopamine signaling in C. elegans: possible involvement of dopaminine in the regulation lifespan. Aging. Oct 21; 1(10):870-4



Fujisawa K., Wrana J.L., Culotti J.G. (2007). The slit receptor EVA-1 coactivates a SAX-3/Robo mediated guidance signal in C. elegans.  Science. Sep 28;317(5846):1934-8.

Zheng, H., Coudiere, L., Camia, C., Colavita, A., Culotti, J.G., and Merz, D.C. (2007). C. elegans encodes novel nuclear proteins that regulate responses to UNC-6/netrin guidance cues. Developmental Biology. 310(1): 44-53.

Levy-Strumpf, N. and Culotti J.G. (2007). VAB-8, UNC-73 and MIG-2 regulate axon polarity and cell migration functions of UNC-40 in C. elegans. Nature Neuroscience. 10(2): 161-168.

Siddiqui, S.S. and Culotti J.G. (2007). Examination of neurons in wild type and mutants of Caenorhabditis elegans using antibodies to horseradish peroxidase. Journal of Neurogenetics Oct-Dec;21(4):271-89



Steven, R., Zhang, L., Culotti, J.G. and T. Pawson. (2005). The UNC-73/Trio RhoGEF-2 domain is required in separate isoforms for the regulation of pharynx pumping and normal neurotransmission in C. elegans. Genes and Development.  19(17): 2016-2029.

Dalpe, G., Brown, L. and J.G. Culotti. (2005). Vulva morphogenesis involves attraction of Plexin-1 expressing primordial vulva cells to Semaphorin-1a sequentially expressed at the vulva midline. Development. 132(6): 1387-1400.



Dalpe, G., Zhang, J.-J., Zheng, H. and J.G. Culotti. (2004). Conversion of cell movement responses to Semaphorin-1 and Plexin-1 from attraction to repulsion by lowered levels of specific Rac GTPases in C. elegans. Development. 131(9): 2073-2088.

Ikegami, R., Zheng, H., Ong, S-H. and J.G. Culotti. (2004). Integration of semaphorin-2A/MAB-20, ephrin-4, and UNC-129 TGF-beta signaling pathways regulates sorting of distinct sensory rays in Caenorhabditis elegans.  Developmental Cell. 6(3): 383-395.

Sanyal, S., Wintle, R.F., Kindt, K.S., Nuttley, W.M., Arvan, R., Fitzmaurice, P., Bigras, E., Merz, D.C., Hebert, T.E., Van Der Kooy, D., Schafer, W.R., Culotti, J.G. and H.H. Van Tol. (2004). Dopamine modulates the plasticity of mechanosensory responses in Caenorhabditis elegans. European Molecular Biology Organization Journal. 23(2): 473-482.



Kubiseski, T.J., Culotti, J.G. and T. Pawson. (2003). Functional analysis of the Caenorhabditis elegans UNC-73B PH domain demonstrates a role in activation of the Rac GTPase in vitro and axon guidance in vivo. Molec. Cell Biol. 23(19): 6823-6835.

Merz, D.C., Alves, G., Kawano, T., Zheng, H. and J.G. Culotti. (2003). UNC-52/perlecan affects gonadal leader cell migrations in C. elegans hermaphrodites through alterations in growth factor signaling. Dev. Biol. 256(1): 173-186.



Killeen, M., Tong, J.-F., Krizus, A., Steven, R., Scott, I., Pawson, T. and J.G. Culotti. (2002). UNC-5 function phosphorylation of cytoplasmic tyrosine 482, but its UNC-40 independent functions also require a region between the ZU-5 and death domains. Dev. Biol. 251(2): 348-366.

Ginzburg, V., Roy, P. and J.G. Culotti. (2002). Semaphorin-1a and semaphorin-1b are required for correct epidermal cell positioning and adhesion during morphogenesis in C. elegans. Development. 129(9): 2065-2078.

Warren, C.E., Krizus, A., Roy, P.J., Culotti, J.G. and J.W. Dennis. (2002). The Caenorhabditis elegans gene, gly-2, can rescue the N-acetylglucosaminyltransferase V mutation of Lec4 cells. J. Biol. Chem. 277(25): 22829-22838.

Degtyareva, N.P., Greenwell, P., Hofmann, E.R., Hengartner, M.O., Zhang, L., Culotti, J.G. and T.D. Petes. (2002). Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity.  Proc. Natl. Acad. Sci. 99(4): 2158-2163.



Merz, D., Zheng, H. and J.G. Culotti. (2001). Multiple signaling mechanisms of the UNC-6/netrin receptors UNC-5 and UNC-40/dcc in vivo. Genetics. 158(3): 1071-1080.

Tong, J., Killeen, M., Steven, R., Binns, K.L., Culotti J.G. and T. Pawson. (2001). Netrin stimulates tyrosine phosphorylation of the UNC-5 family of netrin receptors and induces Shp2 binding to the RCM cytodomain. J. Biol. Chem. 276(44): 40917-40925.

Hao, J.C., Yu, T., Fujisawa, K., Culotti, J.G., Barstead, R., Gengyo-Ando, K., Mitani, S., Tessier-Lavigne, M. and C.I. Bargmann. (2001). C. elegans slit acts in midline, dorsal-ventral, and anterior-posterior guidance via the SAX-3/Robo. Neuron. 32(1): 25-38. 



Nash, B., Colavita, A., Zheng, H., Roy, P.J. and J.G. Culotti. (2000). The forkhead transcription factor UNC-130 is required for the graded spatial expression of the UNC-129 TGF-beta guidance factor in C. elegans. Genes & Development. 14(19): 2486-2500.

Nakashiba, T., Ikeda, S., Nishimura, K., Tashiro, T., Honjo, T., Culotti, J.G. and S. Itohara. (2000). Netrin-G1: a novel glycosyl phosphatidylinositol-linked mammalian netrin that is functionally divergent from the classical netrins.  J. Neurosci. 20(17): 6540-6550.

Merz, D.C. and J.G. Culotti. (2000). Genetic analysis of growth cone migrations in Caenorhabditis elegans. J. Neurobiol. 44(2): 281-288.

Su, M.-W., Merz, D.C., Killeen, M.T., Zhou, Y., Zheng, H., Kramer, J.M., Hedgecock, E.M. and J.G. Culotti. (2000). Regulation of the UNC-5 Netrin receptor initiates the first re-orientation of migrating distal tip cells in C. elegans.  Development. 127(3): 585-594.

Roy, P.J., Zheng, H., Warren, C.E. and J.G. Culotti. (2000). mab-20 encodes a Semaphorin-2a and is required to prevent ectopic contacts between cells of similar type during epidermal morphogenesis in C. elegans. Development. 127(4): 755-767.







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