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 Woodgett Lab 

 

CD40 signalling

 
 

CD40 is a receptor related to the TNF and IL-1 receptors which binds CD40 ligand and elicits a variety of effects in B cells. References dealing with CD40 activation of the stress-activated protein kinase pathways:

  • Berberich, I., Shu, G., Siebelt, F., Woodgett, J.R., Kyriakis, J.M. and Clarke, E.A. (1996) Crosslinking CD40 on B cells induces stress-activated protein kinases but not mitogen activated protein kinases. EMBO J. 15, 92-101.
  • Sakata, N., Patel. H. R., Terada, N., Aruffo, A., Johnson, G. L. and Gelfand, E. W. (1995) Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells J. Biol. Chem. 270, 30823
 

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